Pharmaceutical Organic Chemistry (Part-I)
  by Ramarao Nadendla
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   ISBN 978-81-85731-56-8; 2nd Ed. 2011; pp.viii+280;

   Delhi price: 250      Outside Delhi price: 265      Overseas price : 350

 About The Book  

The book provides comprehensive yet concise chemistry of heterocyclic compounds and natural products as per the syllabi of the B.Pharma course prescribed by AICTE and various Indian Universities. The topics covered include polynuclear aromatic hydrocarbons, unsaturated carbonyl compounds, stereochemistry, pericyclic reactions, chemistry of heterocyclic compounds, carbohydrates, glycosides, lipids, aminoacids and proteins, nucleic acids, alkaloids, purines and important reagents employed in organic syntheses. It also contains problems at the end of book, which are designed to develop proficiency through practice. The subject matter will be of interest to the students and teachers of pharmacy and general science courses.


1. Introduction

2. Polynuclear Aromatic Hydrocarbons
    1. Naphthalene
    2. Anthracene
    3. Phenanthrene
    4. Diphenylmethane
    5. Triphenylmethane

3. Unsaturated Carbonyl Compounds

4. Reagents in Organic Synthesis
    1. Aluminium isopropoxide
    2. Aluminium-t-butoxide
    3. Sodamide
    4. Polyphosphoric acid
    5. Sodium borohydride
    6. Lead tetra-acetate
    7. Lithium aluminium hydride (LIAIH4)
    8. N-Bromosuccinimide (NBS)

5. Stereoisomerism
    1. Structural isomerism
    2. Geometrical isomerism
    3. Stereochemistry of oximes
    4. Optical isomerism
    5. Stereochemistry of biphenyl compounds
    6. Conformational isomerism
    7. Nucleophilc substitution of alkyl halides
    8. Alkene addition reactions

6. Pericyclic Reactions
    1. Introduction and principle categories
    2. Orbital symmetry

7. Heterocyclic Compounds
    1. Introduction
    2. Importance of heterocyclic compounds
    3. Nomenclature
    4. Five-membered heterocyclics with one hetero atom
        (a) Furan
        (b) Pyrrole
        (c) Thiophene
    5. Five-membered heterocyclics with two hetero atoms
        (a) Pyrazoles
        (b) Imidazoles
        (c) Oxazole and isoxazole
        (d) Thiazoles
    6. Six-membered heterocyclics with one hetero atom
        (a) Pyridine
     7. Six-membered heterocyclics with two hetero atoms
        (a) Pyrazine
        (b) Pyrimidines
        (c) Pyridazines
    8. Seven-membered heterocyclics
        (a) Oxepines
        (b) Azepine
    9. Condensed heterocyclics
        (a) Quinoline and isoquinoline
        (b) Indole
        (c) Acridine
        (d) Phenothiazines
        (e) Benzofuran
        (f) Benzimidazole

8. Carbohydrates
    1. Introduction and classification
    2. Glucose
    3. Fructose
    4. Sucrose
    5. Lactose
    6. Maltose
    7. Interconversions of monosaccharides
    8. Starch and starch derivatives
    9. Cellulose and cellulose derivatives
    10. Qualitative analysis of carbohydrates

9. Glycosides
    1. Introduction and classification
    2. Synthesis of methyl glycosides
    3. Extraction of glycosides
    4. Cardiac glycosides
    5. Anthraquinone glycosides
    6. Salicin
    7. Amygdalin

10. Lipids (Fats, Oils and Waxes)
    1. Introduction and classification
    2. Extraction, physical and chemical properties
    3. Analysis of fats and oils
    4. Waxes

11. Amino Acids and Proteins
AMINO ACIDS  1. Introduction and classification
                    2. Essential amino acids
                    3. Synthesis of amino acids
                    4. Properties of amino acids
                    5. Peptides
PROTEINS       6. Introduction and classification of protiens
                    7. General properties of proteins
                    8. Structure of proteins
                    9. Qualitative tests for proteins
                   10. Chemistry of insulin
                   11. Chemistry of oxytocin

12. Nucleic Acids
    1. Introduction and classification and functions of nucleic acids
    2. Structure of nucleic acids
       (a) Structure of DNA    (b) Structure of RNA
    3. Biological functions of Nucleic acids

13. Alkaloids
    1. Introduction and occurrence
    2. Isolation
    3. General properties
    4. Classification
    5. General methods to determine structure
    6. Ephedrine
    7. Coniine
    8. Nicotine
    9. Papaverine
    10. Atropine
    11. Cinchona alkaloids
    12. Quinine
    13. Reserpine
    14. Morphine
    15. Morphine analogues—structure activity relationships

14. Purines
    1. Introduction, classification and chemistry of purine
    2. Chemistry of uric acid
    3. Caffeine
    4. Theophylline
    5. Theobromine
    6. Interrelationship of uric acid and xanthine bases
    7. Uses of xanthine bases
    8. Official preparations of xanthine derivatives

APPENDIX-I   Practice Questions
APPENDIX-II   Objective Type of Questions with Answers