About The Book
New chapters like metabolism of nucleoproteins and nucleic acids, heme metabolism with clinical aspects of hepatitis, concept of free radicals and antioxidants and acquired immunodeficiency syndrome have been added. The chapters on analytical techniques and automation will be useful.
At one time biochemistry formed a very small part of the B.Pharm. course but with the progress made in the understanding of the mechanism of drug action, the knowledge of biochemistry has become of vital importance. Pharmacokinetics of a drug deter¬mines the onset, duration and termination of the drug action and without a biochemical background it is near impossible to under¬stand pharmacokinetics. Realising all this the Pharmacy Council of India introduced the subject of Biochemistry in the new Diplo¬ma course in Pharmacy where the students admitted have the same basic admission qualification as per the B.Pharm. or M.B.B.S. i.e. those who have done 10+2 at the school level.
The book has been written to meet the requirements of both the Diploma in Pharmacy and the B.Pharm. courses, since there is very little difference in the contents of both the courses and even the emphasis of different areas of biochemistry are essentially the same. Biochemical processes related to the mechanism of action of drug and its metabolism and drug-drug interactions have been highlighted. The course content of ‘Clinical Pathology’ along with ‘Practicals’ of both biochemistry and clinical pathology. We feel that the book will be found interesting by the medical students also.
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Content
PART I — THEORY
BIOCHEMISTRY
1. Introduction
2. Carbohydrates
3. Lipids
4. Amino acids, Peptides and Proteins
5. Nucleosides and Nucleotides
6. Enzymes
7. Vitamins
8. Biologic Oxidation
9. Water Balance
10. Mineral Metabolism
11. Carbohydrate Metabolism
12. Lipid Metabolism
13. Protein Metabolism
14. Biotransformation
CLINICAL PATHOLOGY
15. Introduction to Pathology of Blood
16. Abnormal Constituents of the Urine
PART II — PRACTICALS
1. Identification of an Unknown Substance of Physiological Importance
1.1 Scheme for Identification of an Unknown Carbohydrate
1.2 Scheme for Identification of an Unknown Protein
2. Colorimetry
3. Quantitative Determination of Blood Constituents
3.1 Blood Glucose
3.2 Serum Cholesterol (Total)
3.3 Serum Calcium
3.4 Urine Calcium
3.5 Serum Urea
3.6 Serum Creatinine
3.7 Urine Creatinine
3.8 Serum Bilirubin
3.9 Serum Alkaline Phosphatase
3.10 Serum Acid Phosphatase
3.11 Serum Lipase
3.12 Serum Amylase (Diastase)
3.13 SGOT and SGPT (Colorimeteric Method)
4. Normal Urine
5. Examination of Pathological Urine
6. Sputum Examination
7. Examination of Feces
8. Withdrawal of Blood Sample and Practice in Injecting Drugs
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