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About The Book
This book is now a classic one and an important resource for the study on the subject. The revised 3rd edn (2012) makes earlier books obsolete.
A new Chapter on “Biotechnologically Derived Drugs” introduces the essentials of the emerging field of therapeutics. The Chapter 2 on “Chemical Naming and Graphics of Organic Drugs” provides the key to chemical structures and “structural” interconnectivity of different classes of drugs. It also describes 3-letter and 1-letter symbols used for each amino acid in naming polypeptides which are not generally available in chemistry books.
The Chapter 3 on “International Nonpropriety Names (INNs)” is useful for knowing the “medicinal” interconnectivity of drugs and their therapeutic usage.
The Chapters (44) that follow present a comprehensive overview of the design, structure-activity relationship studies and development of the different classes of drugs, with focus on drugs official in Indian and the British Pharmacopoeia, describing also briefly the essentials of their commonly used synthesis or methods of preparation and the pharmacopoeial specifications.
The text ends with the Glossary of Medical Terms and of the Terms used in Medicinal Chemistry to understand all that happens with and around drugs. An exhaustive Index offers easy location of information.
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1. Introduction
2. Chemical Naming and Graphics of Organic Drugs
3. International Nonproprietary Names (INNs)
4. Physicochemical and Stereochemical Aspects and Drug Action
5. Pharmacokinetics
6. General Anaesthetics
7. Local Anaesthetics
8. Hypnotics and Sedatives
9. Antiepileptic Drugs
10. Opioid Analgesics
11. Antitussives
12. Psychoactive Drugs
13. Central Nervous System Stimulants
14. Methylxanthines
15. Drugs for Parkinson's Disease
16. Sympathomimetic Drugs
17. Cholinergic and Anticholinesterase Agents
18. Anticholinergics (Antimuscarinics) : Antispasmodic and Antiulcer Drugs
19. Skeletal Muscle Relaxants
20. Antihistamines
21. Nonsteroidal Antiinflammatory Agents and Analgesic-Antipyretics
22. Cardiovascular Agents
23. Diuretics
24. Anticoagulant, Antiplatelet and Haemostatic Drugs
25. Oxytocics
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26. Hypoglycaemic Agents
27. Thyroid and Antithyroid Drugs
28. Prostaglandins and Other Eicosanoids
29. Steroids and Related Drugs
30. Chemical Contraceptives
31. Anthelmintics
32. Antimalarials
33. Antiprotozoal Agents
34. Sulphonamides
35. Antibiotics
36. Quinolones and Urinary Tract Antiseptics
37. Antimycobacterial Agents
38. Antifungal Drugs
39. Antiviral Agents
40. Antineoplastic Agents
41. Agents Affecting the Immune Response
42. Vitamins
43. Diagnostic Agents
44. Insecticides and Insect Repellents
45. Disinfectants and Antiseptics
46. Organic Pharmaceutical Aids
47. Biotechnologicaly Derived Drugs
APPENDIX I — Glossary of Medical Terms
APPENDIX II — Glossary of Terms used in Medicinal Chemistry
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