About The Book
The course content in subject Inorganic Pharmaceutical Chemistry has been designed to meet objectives that upon completion of this course student shall be able to know the sources of impurities and methods to determine the impurities in inorganic drugs and pharmaceuticals and understand the medicinal and pharmaceutical importance of inorganic compounds.
While describing an inorganic compound or a group, an attempt has been made for providing rational for their use, contraindications, incompatibilies where appropriate, the official use and alternative uses, if any. The matter regarding the Assays and Limit Tests shall also supplement the practical work.
The content is developed in simple language and easy-to-understand manner.
Content
1. INTRODUCTION
Introduction
Historical development
Quality Control of Drugs and Pharmaceuticals
Impurities in Pharmacopoeial Substances
Assay
Gravimetric Methods
Volumetric Methods
Acidimetry and Alkalimetry type
Oxidation-Reduction
Iodometric and Iodimetric type
Precipitation type
Complexometric type
Limit tests for impurities
Chlorides
Sulphates
Iron
Lead
Heavy metals
Arsenic
Modified tests
Identification tests for cations and anions as per I.P. 2010
2. COMMON INORGANIC PHARMACEUTICAL COMPOUNDS
Common Inorganic Pharmaceutical Compounds
Acid, Bases, and Buffers
Buffer Solutions and Buffer Equations
Buffer Capacity
Buffer Isotonic Solution
Official Buffers
Boric Acid
Hydrochloric Acid
Strong Ammonium Hydroxide
Calcium Hydroxide
Sodium Hydroxide
Major Intra- and Extra-cellular Electrolytes
Electrolyte Imbalance and Replacement Theory
Sodium Chloride
Potassium Chloride
Calcium Gluconate
Physiological Acid-Base Balance
Acid-Base Regulation by Electrolytes
Sodium Acetate
Potassium Acetate
Sodium Bicarbonate Injection
Sodium Citrate
Potassium Citrate
Sodium Lactate and Injection
Ammonium Chloride and Injection
Combination of oral electrolyte powders and solutions
Dental Products
Sodium Fluoride
Stannous Fluoride
Calcium carbonate
Sodium Metaphosphate
Dicalcium Phosphate
Strontium Chloride
Role of fluoride in treatment of dental caries
Zinc Eugenol Cement
3. GASTROINTESTINAL AGENTS
Gastrointestinal Agents
Gastric Acidifiers
Ammonium Chloride
Antacids
Sodium Bicarbonate
Aluminium Hydroxide Gel
Aluminium Phosphate
Calcium Carbonate
Magnesium Carbonate
Magnesium Oxide
Magnesium Trisilicate
Magnesium Hydroxide Mixture
Protectives and Adsorbents
Bismuth Subcarbonate
Light Kaolin
Saline cathartics
Sodium Potassium tartrate
Magnesium Sulphate
Sodium Orthophosphate
Bentonite
Topical Agents
Protectives
Talc
Zinc Oxide
Calamine
Zinc Stearate
Titanium Dioxide
Silicone Polymers
Antimicrobials and Astringents
Hydrogen Peroxide
Potassium Permanganate
Chlorinated Lime
Iodine
Solutions of Iodine
Povidine Iodine
Boric Acid
Borax
Silver Nitrate
Mild Silver Protein
Mercury
Yellow Mercuric Oxide
Ammoniated Mercury
Zinc Undecylenate
Sodium Antimony Gluconate
Sulphur and its Compounds
Precipitated Sulphur
Sublimed Sulphur
Selenium Sulphide
4. EXPECTORANTS AND EMETICS
Expectorants and Emetics
Ammonium chloride
Potassium iodide
Antimony potassium tartrate
Copper Sulphate
Sodium potassium tartrate
Antidotes
Sodium Thiosulphate
Sodium nitrite
Astringents
Alum
Zinc sulphate
Haema Tinics and Official Compounds of Iron, Iodine, and Calcium
Ferrous sulphate
Ferrous Gluconate
lodine
Antioxidants
Hypophosphorous acid
Sulphur dioxide
Sodium bisulphite
Sodium meta-bisulphite
Nitrogen
Inhalants
Oxygen
Carbon Dioxide
Nitrous oxide
Respiratory stimulants
Ammonium carbonate
5. RADIOPHARMACEUTICALS AND CONTRAST MEDIA
Radio-pharmaceuticals and Contrast Media Radiopharmaceuticals
Structure of an atom
Radioactivity-Alpha, Beta, and Gamma Radiations
Biological effects of radiation
Measurement of radioactivity
G. M. Counters
Applications of radioisotopes
Handling and Storage of radioactive Materials
Radiopaque/Contrast Media
Barium sulphate
Sodium Iodide
APPENDIX: Glossary of Chemical, Pharmaceutical and Medical Terms
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