Physical Pharmaceutics-I - Vallabh Prakashan

History of pharmacy in India | Order Now (Email) |

Physical Pharmaceutics-I
by C.V.S. Subrahmanyam

Find Books by Course
Find Books by Cover








	About The Book
	Contents
	Reviews
	Related Books
	Order Now by Email

	ISBN 978-93-85529-20-7; 1st Ed. 2019; pp. viii+552 Delhi price: 400 Outside Delhi price: 420 Overseas price : 1200

About The Book Pharmacy Council of India has introduced uniform B.Pharm syllabus throughout the country and the nomenclature Physical Pharmaceutics-I pertains to Semester III (vide no. 6, 7 and 8 of the Bachelor of Pharmacy course regulations 2014) throughout India. The present title is a continuation of earlier title Essential of Physical Pharmacy. The title ‘Physical Pharmaceutics-I’ is to understand the various physical and physicochemical properties of the substances (drugs and excipients), which allows the pharmacist to select the right kind of substance for the manufacture of the dosage form. These also enable to design the right kind of environment desirable in the production and storage of the medicament. The physical and chemical principles and their impact on biological activity are important. Applications are separated and highlighted. Special emphasis is on: 1. Application of principles 2. A number of illustrations on the lines of concept mapping 3. Comment type questions and answers 4. MCQs and key and question bank This book will also serve as a ready reference for the industrial pharmacist also.
Content
Chapter 1. SOLUBILITY PHENOMENON Mechanisms of Interactions—Intermolecular Forces Factors Influencing the Intermolecular Forces Classification of Solvents for the Solubility Methods of Expressing Solubility Question Bank Chapter 2. SOLUBILITY OF SOLIDS IN LIQUIDS Determination of Solubility of Solids in Liquids Factors Influencing Solubility of Drugs Theories of Solutions Solubility Parameters Question Bank Chapter 3. DRUG DISSOLUTION Dissolution-Drug Absorption Dissolution-Tablets and Capsules Theories of Dissolution Mathematical Treatment - Dissolution Factors Influencing Dissolution Dissolution Test Apparatus Vitro-In Vivo Correlations of Dissolution Powder Dissolution—The Hixson Crowell Cube Root Law Question Bank Chapter 4. DIFFUSION Steady State Diffusion Methods and Procedures Transport of Drugs Across Gastrointestinal Tract Diffusion Controlled Release—Higuchi Equation Biopharmaceutics Classification System Question Bank Chapter 5. SOLUBILITY OF GASES IN LIQUIDS Factors Influencing Solubility of Gases in Liquids Ostwald’s Solubility Coefficient Question Bank Chapter 6. SOLUBILITY OF LIQUIDS IN LIQUIDS Miscible Liquids Ideal Solutions Non-ideal Solutions or Real Solutions Question Bank Chapter 7. PARTIALLY MISCIBLE LIQUIDS Phenol—Water System Triethylamine—Water System Nicotine—Water System Influence of Foreign Substances Method of Determination Question Bank Chapter 8. DISTRIBUTION LAW Measurement of Partition Coefficient Influence of Molecular Association on Partition Coefficient Influence of Dissociation on Partition Coefficient Applications Question Bank Chapter 9. GASEOUS STATE Ideal Gas Equation Real Gases-van der Waals Equation Dalton’s Law of Partial Pressures Graham’s Law of Diffusion Question Bank Chapter 10. LIQUID STATE Characteristic Properties of Liquids Liquefaction of Gases Supercritical Fluids Liquid Crystals (Meso) Phase Liquid Complexes Micellar Solubilization Aerosols—Inhalers Question Bank	Chapter 11. SOLID STATE Classification Crystals and Crystal Systems Laws of Crystallography Crystal Habit Physical States of Drug Solids Characterization of Crystals Hygroscopicity—Moisture-Humidity Question Bank Chapter 12. PHYSICOCHEMICAL PROPERTIES OF DRUG MOLECULES Group Contribution Methods Dielectric Constant Dipole Moment Induced Polarizability—Induced Dipole Moment Refractive Index and Molar Refraction Optical Rotation Dissociation and Dissociation Constant Methods of Determining Dissociation of Constant Question Bank Chapter 13. SURFACE AND INTERFACIAL PHENOMENA General Principles Surface and Interfacial Tensions-Methods Energetics of Liquid Surfaces Spreading Coefficient Adsorption at Liquid Interfaces Adsorption at Solid Interfaces Electrical Properties of Interfaces Question Bank 14. SORENSEN’S PH SCALE The pH Indicators Measurement of pH Question Bank 15. BUFFER SOLUTIONS Buffer Systems—Composition and Examples Buffer Action—Mechanisms Buffer Equation—Henderson-Hasselbalch Equation Buffer Capacity Buffers in Biological Systems Factors Influencing pH of a Buffer Solution Preparation of Buffer Solutions Question Bank 16. BUFFERED ISOTONIC SOLUTIONS Definitions of Solutions Relating to Tonicity Methods of Adjusting the Tonicity Question Bank 17. COMPLEXATION AND PROTEIN BINDING Metal Complexes Organic Molecular Complexes Inclusion Complexes Analysis of Complexes—Methods Protein Binding Question Bank APPENDIX-I : Answers to the Comments APPENDIX-II :Answers to Numerical Problems APPENDIX-III : Key to the MCQs APPENDIX-IV : Definitions and Meanings APPENDIX-V : All In Twos—Know Them Well APPENDIX-VI : Glossary of Symbols Appendix-VII : Bibliography Appendix-VIII : Greek Alphabets and Multiplication of Units Appendix-IX : Some notations of Units and their Abbreviations in SI units Appendix-X : Interconversion of Units